Format

Send to

Choose Destination
J Pediatr. 2004 Sep;145(3):365-72.

Neuropsychological outcome of infant heart transplant recipients.

Author information

1
Department of Pediatrics, Division of Child Neurology, Loma Linda University, Loma Linda, CA 92350, USA.

Abstract

OBJECTIVE:

To assess long-term neuropsychological outcomes of infant heart transplant recipients.

STUDY DESIGN:

Fifty-five children (mean age, 6.4 years) with a primary diagnosis of hypoplastic left heart syndrome or other cardiac disorders participated in the study. Six areas of risk were assessed (birth; preoperative, intraoperative, and postoperative status; long-term medical complications; and socioeconomic factors). Neuropsychological evaluations included the following: Wechsler Scales of Intelligence, Wechsler Individual Achievement Test, Berry Visual Motor Integration Scale, Comprehensive Evaluation of Language Function, and Achenbach Child Behavioral Checklist.

RESULTS:

Intellectual functioning scores revealed a mean full-scale IQ of 81 +/- 19. Intraoperative and postoperative variables (bypass time, hospital course, and lowest posttransplant pH), long-term medical complications (serious infections and posttransplant surgical procedures), and socioeconomic factors were associated with cognitive functioning. Visual-motor functioning was also related to bypass and total support time.

CONCLUSIONS:

Long-term outcomes reveal low-average neuropsychological functioning and are related to intrasurgical-postsurgical, long-term medical, and socioeconomic factors. The neuropsychological and psychosocial functioning of infant heart transplant recipients will be important to address as they mature during adolescence and adulthood.

PMID:
15343193
DOI:
10.1016/j.jpeds.2004.05.047
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center