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J Biomech Eng. 2004 Jun;126(3):363-70.

Effect of a lipid pool on stress/strain distributions in stenotic arteries: 3-D fluid-structure interactions (FSI) models.

Author information

1
Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609, USA. dtang@wpi.edu

Abstract

Nonlinear 3-D models with fluid-structure interactions (FSI) based on in vitro experiments are introduced and solved by ADINA to perform flow and stress/strain analysis for stenotic arteries with lipid cores. Navier-Stokes equations are used as the governing equations for the fluid. Hyperelastic Mooney-Rivlin models are used for both the arteries and lipid cores. Our results indicate that critical plaque stress/strain conditions are affected considerably by stenosis severity, eccentricity, lipid pool size, shape and position, plaque cap thickness, axial stretch, pressure, and fluid-structure interactions, and may be used for possible plaque rupture predictions.

PMID:
15341174
DOI:
10.1115/1.1762898
[Indexed for MEDLINE]

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