Format

Send to

Choose Destination
Indian J Exp Biol. 2004 Jul;42(7):686-90.

Effect of lupeol isolated from Crataeva nurvala Buch.-Ham. stem bark extract against free radical induced nephrotoxicity in rats.

Author information

1
Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal 576 104, India. annieshirwaiker@yahoo.com

Abstract

Lupeol, isolated from Crataeva nurvala stem bark in doses 40 and 80 mg/kg body weight, po, for 10 days, decreased the concentration of blood urea nitrogen, creatinine and lipid peroxidation and increased glutathione and catalase activities in cisplatin (5 mg/kg body weight, ip) induced nephrotoxicity in rats. The increased glutathione and catalase activities are indicative of antioxidant properties of lupeol.

PMID:
15339033
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center