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J Nutr. 2004 Sep;134(9):2464S-2468S.

Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses.

Author information

1
Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA.

Abstract

Fatty acid binding proteins (FABPs) are members of a highly conserved family of proteins with the task of protecting a cell's delicate lipid balance. Yet they fail when faced with metabolic or inflammatory stress, turning the cytosol into an inhospitable environment with less than ideal outcomes. This review will focus on how FABPs direct lipid traffic and simultaneously control inflammatory and metabolic pathways under the pressures of the Metabolic Syndrome.

PMID:
15333743
PMCID:
PMC4027055
DOI:
10.1093/jn/134.9.2464S
[Indexed for MEDLINE]
Free PMC Article

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