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J Chemother. 2004 Aug;16(4):343-6.

PER-1 production in a urinary isolate of Providencia rettgeri.

Author information

1
SSK Educational Hospital Clinical Microbiology, Ankara, Turkey. gulbahkar@hotmail.com

Abstract

A Providencia rettgeri strain resistant to extended-spectrum cephalosporins and intermediate to aztreonam was isolated from the urine of a patient hospitalized in the urology clinic of SSK Educational Hospital in Ankara. Clavulanic acid restored the activity of extended-spectrum cephalosporins, suggesting that the strain was harboring an extended-spectrum beta-lactamase. Since the PER-1 enzyme is widespread in Turkey, and had been already detected in a related species such as Proteus mirabilis, the Providencia strain was suspected of harboring a PER-1 enzyme, which was indeed detected by PCR. This is the first description in a P. rettgeri isolate of a PER-1 enzyme which is widespread among Acinetobacter baumanni and Pseudomonas aeruginosa strains in Turkey.

PMID:
15332708
DOI:
10.1179/joc.2004.16.4.343
[Indexed for MEDLINE]

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