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Nat Struct Mol Biol. 2004 Sep;11(9):812-5.

Combinatorial control of gene expression.

Author information

1
Gene Expression Program, European Molecular Biology Laboratory, 69117 Heidelberg, Germany. remenyi@itsa.ucsf.edu

Abstract

Revealing the molecular principles of eukaryotic transcription factor assembly on specific DNA sites is pivotal to understanding how genes are differentially expressed. By analyzing structures of transcription factor complexes bound to specific DNA elements we demonstrate how protein and DNA regulators manage gene expression in a combinatorial fashion.

PMID:
15332082
DOI:
10.1038/nsmb820
[Indexed for MEDLINE]

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