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Br J Neurosurg. 2004 Jun;18(3):293-7.

Isolated intracranial Rosai-Dorfman disease mimicking meningioma in a child.

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Department of Neurosurgery, Royal Manchester Children's Hospital, Pendlebury, Manchester, UK.


A 9-year-old boy presented with a 12-month history of headaches and recent grand mal seizures. Computed tomography and magnetic resonance imaging of the brain revealed an enhancing right frontal convexity lesion. The preoperative diagnosis was meningioma. However, histological examination was diagnostic of Rosai-Dorfman disease. Rosai-Dorfman disease confined to the intracranial compartment is very rare, of 34 reported cases only one presented in the first decade. Optimal treatment has not been established, but complete surgical resection alone seems effective and allows histological distinction from meningioma.

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