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Nat Genet. 2004 Sep;36(9):952-4. Epub 2004 Aug 22.

Genomic segmental polymorphisms in inbred mouse strains.

Author information

1
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

Abstract

By analyzing genomic copy-number differences using high-resolution mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between inbred strains of mice. The identification of these apparently common segmental polymorphisms suggests that these differences can contribute to genetic variability and pathologic susceptibility.

PMID:
15322544
DOI:
10.1038/ng1417
[Indexed for MEDLINE]

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