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Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12974-9. Epub 2004 Aug 20.

Drosophila lifespan enhancement by exogenous bacteria.

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1
Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

We researched the lifespan of Drosophila under axenic conditions compared with customary procedure. The experiments revealed that the presence of bacteria during the first week of adult life can enhance lifespan, despite unchanged food intake. Later in life, the presence of bacteria can reduce lifespan. Certain long-lived mutants react in different ways, indicating an interplay between bacteria and longevity-enhancing genes.

PMID:
15322271
PMCID:
PMC516503
DOI:
10.1073/pnas.0405207101
[Indexed for MEDLINE]
Free PMC Article
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