Twenty-five patients with clinical relapse after previous successful angioplasty of iliac or femoro-popliteal arteries were evaluated with repeat angiography. The angiographic patency was 80% despite the clinical symptoms. The discrepancy between the angiographic appearance and the clinical findings was explained by the progress of the general arteriosclerotic vascular disease. Such progression is more important regarding late prognosis than the result of the angioplasty per se.