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Vaccine. 2004 Sep 3;22(25-26):3419-26.

Economic analysis of the 1996-1997 mass measles immunization campaigns in South Africa.

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  • 1Global Immunization Division, National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-05, Atlanta, GA 30333, USA.


To evaluate economic implications of conducting a "catch-up" measles vaccination campaign, we conducted an economic analysis of the 1996-1997 measles immunization campaign in two provinces of South Africa comparing the baseline two-dose routine immunization program to the combined vaccination strategy (routine two-dose immunization program, plus the 1996-1997 campaign). The study findings indicate that the 1996-1997 mass measles immunization campaign was cost-effective in both study provinces, and cost-saving in the province with higher pre-campaign disease incidence and lower routine vaccination coverage. An early investment in effective vaccination strategies that rapidly reduce disease burden apparently results in better returns, both epidemiologically and economically.

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