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Scand J Infect Dis. 2004;36(6-7):523-4.

Chron's disease, rare association with selective IgA immunodeficiency, and development of life-threatening bacterial infections.

Author information

1
Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna 'Alma Mater Studiorum', S. Orsola Hospital, Bologna, Italy. manfredi@med.unibo.it

Abstract

Life-threatening necrotizing fasciitis and relapsing Lemierre syndrome associated with Fusobacterium necrophorum septicaemia occurred in young adults with a moderate Chron's disease and a missed profound IgA deficiency. This unexpected association of a chronic bowel inflammatory syndrome with prominent IgA abnormalities and severe bacterial infection deserves careful attention by physicians faced with young patients with Chron's disease.

PMID:
15307592
DOI:
10.1080/00365540410020190
[Indexed for MEDLINE]

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