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Clin Microbiol Infect. 2004 Aug;10(8):755-7.

Emergence of CTX-M beta-lactamase-producing Enterobacteriaceae in Portugal: report of an Escherichia coli isolate harbouring blaCTX-M-14.

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Laboratório de Microbiologia, Faculdade de Farmácia, Universidade do Porto, 4050-047 Porto, Portugal.


CTX-M beta-lactamases have been reported worldwide since their first description in the early 1990s, and are now endemic in some countries. This report describes an isolate of Escherichia coli producing CTX-M-14 that was recovered from the faecal sample of a healthy subject in Portugal without recent hospital or antibiotic exposure. The presence of ISEcp1, 42 nucleotides upstream of bla(CTX-M-14), and its association with a 100-kb conjugative plasmid, might result in wider dissemination of this enzyme in community and hospital environments in Portugal.

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