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Am J Psychiatry. 1992 Oct;149(10):1393-4.

Anticholinergic effects of drugs commonly prescribed for the elderly: potential means for assessing risk of delirium.

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1
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21204.

Abstract

Anticholinergic effects of the 25 drugs most commonly prescribed for the elderly were measured by radioreceptor assay. Fourteen had detectable anticholinergic drug levels; 10 of these had levels that have been associated with impairments in memory and attention in normal elderly subjects. These data indicate that patients taking multiple medications may be at increased risk for side effects from psychotropic drugs, most of which have anticholinergic effects.

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PMID:
1530077
DOI:
10.1176/ajp.149.10.1393
[Indexed for MEDLINE]
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