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Mov Disord. 2004 Aug;19(8):965-6.

Adrafinil-induced orofacial dyskinesia.

Author information

1
Department of Neurology, The Pierre Wertheimer Neurological Hospital, Lyon, France. stephane.thobois@chu-lyon.fr

Abstract

We describe the first case of orofacial abnormal movements induced by adrafinil, a vigilance promoting agent of the same pharmacological class as modafinil. The dyskinesias did not spontaneously recover despite adrafinil withdrawal for a 4-month period. They were secondly dramatically improved by tetrabenazine, a presynaptic dopaminergic depleting drug which was introduced after the 4-month adrafinil-free period.

PMID:
15300665
DOI:
10.1002/mds.20154
[Indexed for MEDLINE]

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