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Mech Dev. 2004 Sep;121(9):1031-42.

The acquisition of neural fate in the chick.

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1
Department of Molecular Cell Biology, Max-Planck-Institut für biophysikalische Chemie, Am Fassberg 11, 37077 Göttingen, Germany. wittler@molgen.mpg.de

Abstract

Neural development in the chick embryo is now understood in great detail on a cellular and a molecular level. It begins already before gastrulation, when a separation of neural and epidermal cell fates occurs under the control of FGF and BMP/Wnt signalling, respectively. This early specification becomes further refined around the tip of the primitive streak, until finally the anterior-posterior level of the neuroectoderm becomes established through progressive caudalization. In this review we focus on processes in the chick embryo and put classical and more recent molecular data into a coherent scenario.

PMID:
15296969
DOI:
10.1016/j.mod.2004.05.004
[Indexed for MEDLINE]
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