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Rev Assoc Med Bras (1992). 2004 Apr-Jun;50(2):148-52. Epub 2004 Jul 21.

[Ophthalmological findings in HIV infected patients in the post-HAART (Highly Active Anti-retroviral Therapy) era, compared to the pre-HAART era].

[Article in Portuguese]

Author information

1
Departamento de Oftalmologia da Universidade Federal de São Paulo, UNIFESP/EPM, São Paulo, SP.

Abstract

BACKGROUND:

To determine the frequency of the ophthalmological findings in Human Immunodeficience Virus (HIV) infected patients in the post-HAART (Highly Active Anti-retroviral Therapy) era and to compare it to data from the Federal University of São Paulo in the pre-HAART era10,11.

METHODS:

Charts from 200 consecutive patients examined from May 2000 to February 2001 were reviewed.

RESULTS:

From the total of 200 patients, 84 (42%) presented ophthalmological findings related to HIV infection in the first ocular examination: 36 (18%) with Cytomegalovirus retinitis (9 active and 27 inactive), 22 (11%) with ocular toxoplasmosis, (9 active and 13 inactive), 15 (7.5%) with retinal detachment (10 secondary to CMV retinitis, 3 to ocular toxoplasmosis and 2 not determined), 8 (4%) with cataract (5 secondary to CMV retinitis, 1 to ocular toxoplasmosis and 2 not determined), 8 (4%) with cotton wool spots, 6 (3%) with acute retinal necrosis (4 active and 2 inactive) and 3 (1.5%) with intersticial keratitis. All patients with acute retinal necrosis showed T CD4 cells under 100 cells/microL.

CONCLUSION:

The authors identified in the post-HAART era, rise on number of patients with normal ophthalmologic exam and decreased number of cases of CMV retinitis and ocular toxoplasmosis when compared to the pre-HAART era.

PMID:
15286861
DOI:
/S0104-42302004000200029
[Indexed for MEDLINE]
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