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Nat Med. 2004 Aug;10(8):769-71.

Urgently needed: a filter for the HIV-1 vaccine pipeline.

Author information

1
Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, USA. jpm2003@med.cornell.edu

Abstract

Research groups worldwide are trying to make immunogens intended to elicit neutralizing antibody responses as part of a prophylactic vaccine to counter the spread of HIV-1. The relative merits of different designs can only be gauged properly through comparative studies, and particularly by evaluating human or animal antisera under identical, or comparable, conditions. Hence there is a need for assay standardization and for the creation of a centralized testing facility that could distribute consensus protocols and reagents.

PMID:
15286768
DOI:
10.1038/nm0804-769
[Indexed for MEDLINE]

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