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Anal Bioanal Chem. 2004 Aug;379(7-8):913-9. Epub 2004 Jul 20.

Application of luminescent nanocrystals as labels for biological molecules.

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1
Freiburg Materials Research Center (FMF), Stefan-Meier-Str. 21, 79104 Freiburg, Germany.

Abstract

Luminescent semiconductor nanocrystals, so called "quantum dots" (QD), have attracted increasing interest for bioanalytical labeling applications in recent years. This review describes the major optical and (bio)chemical features of this class of label, compared with organic dyes. Different conjugation methods are also discussed and the most important recent applications are presented. An overview over the current state-of-the-art is given, as also is an outlook on possibilities and limitations.

PMID:
15278340
DOI:
10.1007/s00216-004-2706-y
[Indexed for MEDLINE]
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