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Parasitol Today. 1994 Jun;10(6):234-6.

The role of IL-5 in the immune responses to nematodes in rodents.

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Department of Oncology, Kumamoto University Medical School, 2-2-1 Honjo, Kumamoto 860, Japan.


In this review, Masataka Korenoga and Isoo Toda discuss the role of interleukin 5 (IL-5) in immune responses caused by parasitic infections. Recent studies have shown that eosinophilia in parasitic infections is dependent on IL-5. Although eosinophils have been thought to be potent effector cells (from results of experiments, in vitro), their role in protective immunity to parasites is controversial.

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