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Parasitol Today. 1996 Oct;12(10):396-9.

Autoimmunity in chagas disease cardiomyopathy: Fulfilling the criteria at last?

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Transplantation Immunology Laboratory, Instituto do Coração Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.


Here, Jorge Kalil and Edécio Cunha-Neto review the recent evidence for autoimmunity in chronic Chagas cardiomyopathy (CCC) involving molecularly defined antigens and immunopathological mechanisms. They also discuss the criteria for assignment of CCC as an organ-specific autoimmune disease.

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