Send to

Choose Destination
Parasitol Today. 1996 Mar;12(3):108-14.

Karyotype variability in Trypanosoma cruzi.

Author information

Department of Medical Genetics, Biomedical Center, Uppsala University, Box 589, S-751 23 Uppsala, Sweden.


Like many other protozoam parasites, Trypanosoma cruzi (the causative agent of Chagas disease) has a plastic genome. Chromosome size polymorphisms occur in different strains of T. cruzi as well as among clones originating from the same strain, Despite this polymorphism, major interchromosomal rearrangements appear to be rare since several linkage groups of chromosomal markers are well conserved among different T. cruzi strains. In addition, some correlation has been found between karyotype variability and classification by multilocus enzyme electrophoresis. In this review, Jan Henriksson, Lena Aslund and Ulf Petterson discuss the genomic variability and suggest that amplication of repetitive sequences or members of gene families make a major contribution to the chromosomal size variation.


Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center