Format

Send to

Choose Destination
J Infect Dis. 1992 Oct;166(4):874-84.

The 38-kDa protein of Mycobacterium tuberculosis: a review.

Author information

1
Institute of Immunology and Rheumatology, University of Oslo, Norway.

Abstract

This review illustrates that the 38-kDa protein is one of the most important antigens of Mycobacterium tuberculosis. It is actively secreted but partly attached to the surface of the mycobacterial cell by a lipid tail that may also be responsible for binding of carbohydrate to the protein. It is a major constituent of M. tuberculosis culture fluid after growth on the synthetic Sauton medium and occurs in bacille Calmette-Guérin in far lower concentrations. The protein induces B and T cell responses with high specificity for infection with M. tuberculosis and is a prime candidate for development of new diagnostic reagents for tuberculosis.

PMID:
1527425
DOI:
10.1093/infdis/166.4.874
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center