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J Assist Reprod Genet. 2004 Apr;21(4):103-7.

Monozygotic twins and triplets in association with blastocyst transfer.

Author information

1
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

Abstract

PURPOSE:

To compare the incidence of monozygotic twins following blastocyst versus day-3 embryo transfer (ET).

METHODS:

A retrospective analysis of the outcome of assisted reproductive technology (ART) cycles utilizing blastocyst ET during 1999-2000 was compared to a similar group of patients undergoing day-3 ET during 1997-1998.

RESULTS:

Blastocyst ET was used in 75 cycles with 2.0 +/- 2 embryos transferred. The comparison group consisted of 90 cycles with day-3 ET and 3.0 +/- 2 embryos transferred.

CONCLUSIONS:

High pregnancy rates are maintained with blastocyst ET even though fewer embryos are transferred. The rate of monozygotic twins is higher with blastocyst ET than with day-3 ET. This increase may partially negate the benefit of reduced high-order multiple gestations attributed to blastocyst ET.

PMID:
15270208
PMCID:
PMC3455608
[Indexed for MEDLINE]
Free PMC Article
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