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OMICS. 2004 Summer;8(2):106-17.

Integrated analysis of microarray data and gene function information.

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Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, 38103, USA.


Microarray data should be interpreted in the context of existing biological knowledge. Here we present integrated analysis of microarray data and gene function classification data using homogeneity analysis. Homogeneity analysis is a graphical multivariate statistical method for analyzing categorical data. It converts categorical data into graphical display. By simultaneously quantifying the microarray-derived gene groups and gene function categories, it captures the complex relations between biological information derived from microarray data and the existing knowledge about the gene function. Thus, homogeneity analysis provides a mathematical framework for integrating the analysis of microarray data and the existing biological knowledge.

[Indexed for MEDLINE]

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