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Eur J Obstet Gynecol Reprod Biol. 2004 Aug 10;115(2):159-60.

Infectious and inflammatory mechanisms in preterm birth and cerebral palsy.

Author information

1
Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, The Sahlgrenska Academy at Göteborg University, SE-41685, Sweden. bo.jacobsson@obgyn.gu.se

Abstract

OBJECTIVE:

In a thesis examine infectious and inflammatory mechanisms involved in preterm birth and cerebral palsy.

STUDY DESIGN:

Four cross-sectional studies and a case control study.

RESULTS:

Microbial invasion of the amniotic cavity and inflammation in this population of Swedish women in preterm labor and preterm prelabor rupture of membranes was similar to that reported in data from populations with a higher incidence of preterm birth. Our data support an association between antenatal infection/inflammation and cerebral palsy.

CONCLUSIONS:

Infectious and inflammatory mechanisms are involved in preterm birth and cerebral palsy in a population with low incidence of preterm birth.

PMID:
15262348
DOI:
10.1016/j.ejogrb.2003.11.014
[Indexed for MEDLINE]

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