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J Adolesc Health. 2004 Aug;35(2):156-8.

Allergic symptoms and microflora in schoolchildren.

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Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Public Health, Kyoto, Japan.


We studied 867 junior high school children and administered a questionnaire documenting allergic symptoms and environmental variables, and measured Immunoglobulin E serum levels and the immunoglobulin G titers of serum antibody to microflora. A total of 716 subjects were ultimately used for statistics; those with at least two of the following allergic symptoms: asthma, rhinitis, eczema, or food allergy, showed significantly higher IgG titers to Bactroides vulgatus than other groups. This finding suggests that a species of the Bacteroides genus of the intestinal microflora tends to affect the gut issues, but further studies are needed to clarify this.

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