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Nat Neurosci. 2004 Aug;7(8):801-2. Epub 2004 Jul 18.

Abnormal cortical voice processing in autism.

Author information

1
ERM 0205, INSERM-CEA, DRM, DSV, Service Hospitalier Frédéric Joliot, 4, place du General Leclerc, 91406, Orsay, France.

Abstract

Impairments in social interaction are a key feature of autism and are associated with atypical social information processing. Here we report functional magnetic resonance imaging (fMRI) results showing that individuals with autism failed to activate superior temporal sulcus (STS) voice-selective regions in response to vocal sounds, whereas they showed a normal activation pattern in response to nonvocal sounds. These findings suggest abnormal cortical processing of socially relevant auditory information in autism.

PMID:
15258587
DOI:
10.1038/nn1291
[Indexed for MEDLINE]
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