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Curr Opin Neurobiol. 1992 Aug;2(4):479-83.

Neural mechanisms of hyperalgesia.

Author information

1
University of Minnesota, Minneapolis.

Abstract

Hyperalgesia, or enhanced sensitivity to pain, is a symptom often associated with inflammation, nerve injury and various diseases. Although hyperalgesia appears to be mediated by sensitization of peripheral and central pain-signalling neurons, underlying mechanisms of sensitization are not well understood. Recent contributions to our knowledge of the mechanisms underlying hyperalgesia and sensitization are reviewed.

PMID:
1525546
[Indexed for MEDLINE]

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