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Mov Disord. 2004 Jul;19(7):836-838. doi: 10.1002/mds.20086.

Vascular hemichorea/hemiballism and topiramate.

Author information

1
Parkinson's Disease and Movement Disorders Program, Department of Neurosciences, Hospital de ClĂ­nicas, University of Buenos Aires, Buenos Aires, Argentina.

Abstract

Although vascular hemichorea/hemiballism (HC/HB) has been reported to be self-limited, in some cases, it can be irreversible and severely disabling. The standard treatment includes typical and atypical neuroleptics and GABA-mimetic drugs. Topiramate is a new antiepileptic drug possessing a complex mechanism of action, including the enhancement of GABA-mediated inhibition. We describe a 71-year-old patient with HC/HB who markedly improved after topiramate treatment.

PMID:
15254947
DOI:
10.1002/mds.20086
[Indexed for MEDLINE]

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