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J Steroid Biochem Mol Biol. 1992 Sep;43(1-3):223-8.

Progestin-induced fatty acid synthetase in human mammary tumors: from molecular to clinical studies.

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1
Unité INSERM 148 Hormones and Cancer, Montpellier, France.

Abstract

Fatty acid synthetase (FAS) is one of the first well-characterized progestin-induced proteins with available antibodies and cDNA. This paper reviews basic studies on FAS regulation in human breast cancer cell lines and recent data on the possible clinical significance of this new marker of hormone responsiveness in mammary cancer and benign breast diseases.

PMID:
1525062
DOI:
10.1016/0960-0760(92)90211-z
[Indexed for MEDLINE]

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