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Arch Surg. 2004 Jul;139(7):760-5.

Association of Streptococcus bovis bacteremia with colonic neoplasia and extracolonic malignancy.

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1
Department of Surgery, Yale University School of Medicine, New Haven, Conn. 06520, USA.

Abstract

BACKGROUND:

The association between Streptococcus bovis bacteremia and colonic neoplasia is well described; however, the relationship between S bovis and neoplasia outside the colon has not been well evaluated.

HYPOTHESIS:

S bovis bacteremia may be associated with colonic neoplasia and extracolonic malignancy.

DESIGN:

Retrospective review of all documented cases of S bovis bacteremia identified by a search of computerized bacteriology records.

SETTING:

One tertiary referral hospital and 1 community hospital located in the same city.

PATIENTS:

Forty-five patients (41 adults, 4 children) with documented S bovis bacteremia during a 12-year period were identified.

MAIN OUTCOME MEASURES:

Available patient records were reviewed to identify the presence of colonic neoplasia, the use of gastrointestinal endoscopy, and the presence of gastrointestinal or extraintestinal malignancies.

RESULTS:

Seventeen patients (41% of adult patients) underwent colonoscopy. Colonic neoplasia was present in 16 patients (39% of adults), with 3 of these patients having invasive colorectal cancer (7% of adults). Invasive cancer was present in 13 patients (32% of adults). Eight patients had malignant lesions arising within the gastrointestinal tract, and 5 patients had extraintestinal malignancies.

CONCLUSION:

S bovis bacteremia is associated with both colonic neoplasia and extracolonic malignancy.

PMID:
15249410
DOI:
10.1001/archsurg.139.7.760
[Indexed for MEDLINE]

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