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Vaccine. 2004 Jul 29;22(21-22):2757-60.

Limited infection upon human exposure to a recombinant raccoon pox vaccine vector.

Author information

1
USGS National Wildlife Health Center, 6006 Schroeder Road, Madison, WI 53711, USA. tonie_rocke@usgs.gov

Abstract

A laboratory accident resulted in human exposure to a recombinant raccoon poxvirus (RCN) developed as a vaccine vector for antigens of Yersinia pestis for protection of wild rodents (and other animals) against plague. Within 9 days, the patient developed a small blister that healed within 4 weeks. Raccoon poxvirus was cultured from the lesion, and the patient developed antibody to plague antigen (F1) and RCN. This is the first documented case of human exposure to RCN.

PMID:
15246608
DOI:
10.1016/j.vaccine.2004.01.030
[Indexed for MEDLINE]

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