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AIDS Res Hum Retroviruses. 2004 Jun;20(6):666-72.

Identification of a highly divergent HIV type 2 and proposal for a change in HIV type 2 classification.

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Virology Department, H├┤pital Bichat, 75877 Paris 18, France.


We report the complete genome sequence of a highly divergent strain of human immunodeficiency virus type 2 (HIV-2), 96FR12034, identified in France from a patient of West African origin. This lineage, H, represents only the third definitive instance of a monkey-to-human transfer of SIVsm that has given rise to pathogenic HIV-2. As the different "subtypes" of HIV-2 are analogous to the different groups of HIV-1 we propose that HIV-2 subtypes henceforth by renamed groups in agreement with the HIV Nomenclature Committee. The single-strain lineages C to G and the 96FR12034 lineage identified here should be considered only as putative groups until related strains are identified that confirm circulation of these viruses in the human population.

[Indexed for MEDLINE]

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