Format

Send to

Choose Destination
See comment in PubMed Commons below
Dev Cell. 2004 Jul;7(1):9-20.

Muscle building; mechanisms of myotube guidance and attachment site selection.

Author information

1
Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Dr. Bohr-Gasse 3-5, 1030 Vienna, Austria. frank.schnorrer@imba.oeaw.ac.at

Abstract

The complex muscle patterns of higher organisms arise as migrating myoblasts are guided toward and connect with specific attachment sites. We review here the current understanding of myotube migration, focusing on its dynamic nature and the few molecular cues that have been identified to date. Much of this knowledge comes from studies in Drosophila, where powerful methods for in vivo imaging and genetic manipulation can be used to tackle this important but largely unsolved problem in developmental biology.

PMID:
15239950
DOI:
10.1016/j.devcel.2004.06.010
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center