[The effect of amniotic fluid taken from women in labor on the morphofunctional development of fetal and newborn rats]

Zh Evol Biokhim Fiziol. 1992 Jan-Feb;28(1):126-30.
[Article in Russian]

Abstract

Amniotic fluid from women was injected intra-amniotically to rats at the 14th day of pregnancy in a dose 0.3 ml. Morphological and functional parameters of embryonic development of rats and EMG activity of rat puppies at the age of 30-34 days differed from control ones with respect to the degree of maturity and motor disturbances of newborn babies. The data obtained reveal not only evident but also masked forms of motor pathology which was observed in children later, namely to 6-9 months. Chronic motor pathology in rat puppies was unilateral with central motor disturbances in babies being directly related to the degree of these disturbances.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Amnion
  • Amniotic Fluid / physiology*
  • Animals
  • Animals, Newborn
  • Electromyography
  • Embryonic and Fetal Development / drug effects*
  • Embryonic and Fetal Development / physiology
  • Female
  • Humans
  • Injections
  • Labor, Obstetric / physiology*
  • Movement Disorders / etiology
  • Pregnancy
  • Pregnancy Complications / physiopathology
  • Prenatal Exposure Delayed Effects*
  • Rats