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Am J Ophthalmol. 2004 Jul;138(1):158-60.

Duration of the effect of intravitreal triamcinolone acetonide as treatment for diffuse diabetic macular edema.

Author information

1
Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Heidelberg, Germany. Jost.Jonas@ma.augen.uni-heidelberg.de

Abstract

PURPOSE:

To evaluate the duration of the effect of intravitreal triamcinolone acetonide on visual acuity in patients with diffuse diabetic macular edema.

DESIGN:

Clinical interventional case series.

METHODS:

Subjects were 31 patients (38 eyes) with diffuse diabetic macular edema who received an intravitreal injection of 20- to 25-mg triamcinolone acetonide. Mean follow-up time was 13.2 +/- 6.0 months (6.03-25.2 months).

RESULTS:

Visual acuity and intraocular pressure began to increase significantly (P =.003) within the first week, reaching a plateaulike maximum at 1 to 7 months postinjection, returning to baseline values 8 to 9 months postinjection.

CONCLUSIONS:

The effect of an intravitreal injection of approximately 20- to 25-mg triamcinolone acetonide in patients with diffuse diabetic macular edema lasts approximately 7 to 8 months. This information may be helpful in determining the optimal dosage of intravitreal triamcinolone acetonide for the treatment of diffuse diabetic macular edema.

PMID:
15234306
DOI:
10.1016/j.ajo.2004.02.025
[Indexed for MEDLINE]

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