Format

Send to

Choose Destination
Sleep Med Rev. 2004 Aug;8(4):295-308.

Sleep disordered breathing in cystic fibrosis.

Author information

1
Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney NSW, Australia. mareem@galen.med.usyd.edu.au

Abstract

Cough, sleep fragmentation and oxyhaemoglobin desaturation have all been documented during sleep in patients with cystic fibrosis (CF). It has been proposed that repeated episodes of nocturnal hypoxia act as a stimulus for the development of pulmonary hypertension and right ventricular failure, a complication that is associated with a poor prognosis. In addition, sleep disturbance from these events could lead to poor daytime function and quality of life. This review provides a detailed description of the mechanisms underlying sleep disordered breathing in this population, what is known regarding its effects upon daytime function and current treatment options. Most importantly, we review what is needed from future research in this challenging area of care in patients with CF.

PMID:
15233957
DOI:
10.1016/j.smrv.2004.03.004
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center