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Am J Public Health. 2004 Jul;94(7):1089-92.

Improving topical microbicide applicators for use in resource-poor settings.

Author information

1
Program for Appropriate Technology in Health, Seattle, WA 98107, USA.

Abstract

With more than 60 potential microbicides being assessed in preclinical or clinical trials, most attention has been centered on products intended for topical application, with much less research conducted on the applicators that will be used to deliver the microbicides. However, applicator design relates to safety, efficacy, and acceptability. As the foundation for a more systematic approach to evaluating and possibly improving designs for topical microbicide applicators, we conducted a literature review and a series of interviews with microbicide developers, trial investigators, and trial sponsors. Our findings indicate that issues concerning applicator safety, reuse, and cost warrant further investigation.

PMID:
15226124
PMCID:
PMC1448402
[Indexed for MEDLINE]
Free PMC Article

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