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Bioorg Med Chem Lett. 2004 Aug 2;14(15):3861-4.

Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains.

Author information

1
Merck Research Laboratories, Medicinal Chemistry, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA. tim_blizzard@merck.com

Abstract

A series of benzoxathiin SERAMs with bicyclic amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue.

PMID:
15225685
DOI:
10.1016/j.bmcl.2004.05.074
[Indexed for MEDLINE]

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