Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Med. 2004 Jul 1;117(1):39-50.

The antineutrophil cytoplasmic antibody-associated vasculitides.

Author information

1
Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Abstract

Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat. Distinguishing the ANCA-associated vasculitides from other forms of vasculitis or nonvasculitic processes (such as infection) can be particularly difficult. This review describes the clinical and pathologic hallmarks of the ANCA-associated vasculitides, discusses the role of ANCA assays in diagnosis and treatment, and outlines an approach to the evaluation and management of these diseases.

PMID:
15210387
DOI:
10.1016/j.amjmed.2004.02.030
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center