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J Am Geriatr Soc. 2004 Jul;52(7):1045-50.

Functional and cognitive consequences of silent stroke discovered using brain magnetic resonance imaging in an elderly population.

Author information

1
Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.

Abstract

OBJECTIVES:

To evaluate the prevalence of silent stroke and its associated consequences on physical, cognitive, and emotional functioning in an elderly population.

DESIGN:

Population-based cross-sectional survey.

SETTING:

The Memory and Morbidity in Augsburg Elderly project in the Augsburg region of southern Germany.

PARTICIPANTS:

Two hundred sixty-seven community-dwelling persons aged 65 to 83.

MEASUREMENTS:

The presence of silent stroke was determined using magnetic resonance imaging brain scan and a single question asking for physician-diagnosed stroke in each participant. The health effect of silent stroke was assessed using rating scales for self-perceived health status (36-item short-form health survey), activities of daily living (ADLs) and instrumental ADLs, cognitive function, and depression (Center for Epidemiologic Studies Depression scale).

RESULTS:

Just fewer than 13% (12.7%) of participants were affected by silent stroke. Silent stroke was associated with a history of hypertension, heart surgery, and elevated C-reactive protein. Individuals with silent stroke showed impairments on the Mini-Mental State Examination test and in the cognitive domains of memory, procedural speed, and motor performance.

CONCLUSION:

The presence of silent stroke has a considerable effect on cognitive performance in those affected. Determining the presence of silent stroke using brain imaging may contribute to identifying individuals at risk for developing gradual neurological deficits.

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[Indexed for MEDLINE]

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