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J Affect Disord. 2004 Jun;80(2-3):155-62.

Axis I and II comorbidity in a large sample of patients with obsessive-compulsive disorder.

Author information

1
University Medical Center (B.01.206), P.O. Box 85500, 3508 GA Utrecht, The Netherlands.

Abstract

BACKGROUND:

No study has reported yet on the prevalence of both comorbid DSM-IV axis I and personality disorders in a large cohort of OCD patients, and little is known about differences in clinical characteristics between OCD patients with and without comorbid symptoms.

OBJECTIVE:

To examine the cross-sectional prevalence of comorbid DSM-IV axis I, and personality disorders in a population of patients with primary obsessive-compulsive disorder (OCD).

METHOD:

420 outpatients with OCD were evaluated for comorbid pathology, demographic, and clinical characteristics.

RESULTS:

Forty-six percent of the patients were diagnosed with a comorbid disorder. Twenty-seven percent met the criteria for at least one comorbid axis I disorder, 15.6 percent for a comorbid personality disorder, and 20.4 percent for both a comorbid axis I disorder and a personality disorder.

LIMITATIONS:

A limitation of the current study is that the sample was drawn from a psychiatric department specialised in anxiety disorders, which might have underestimated the rate of comorbid diagnoses.

CONCLUSION:

Comorbid diagnoses occur less frequently than would be expected on the basis of comparable comorbidity studies in OCD. Associated axis I comorbidity did not affect clinical severity of OCD, but was related to higher levels of depression and anxiety, whereas axis II comorbidity impaired to a higher extent the overall functioning.

PMID:
15207928
DOI:
10.1016/S0165-0327(03)00056-9
[Indexed for MEDLINE]

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