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AIDS Res Hum Retroviruses. 1992 Jul;8(7):1283-7.

Detection of HIV-1 genome in leukocytes of human colostrum from anti-HIV-1 seropositive mothers.

Author information

1
Institute of Infectious Diseases, University of Rome La Sapienza, Italy.

Abstract

In order to obtain more information about the presence of HIV-1 in mononuclear cells of colostrum, research was carried out on both the HIV-1 genome in the cellular fraction of colostrum and the viral antibody in cell-free colostrum of eight anti-HIV-1 seropositive asymptomatic mothers. In five cases cell fractions of the colostrum harbored HIV-1 genome by DNA-DNA and DNA-RNA in situ hybridization, whereas viral antibody were detected in all cell-free colostrum specimens. The data confirms the colostrum as a possible route of HIV-1 infection.

PMID:
1520540
DOI:
10.1089/aid.1992.8.1283
[Indexed for MEDLINE]

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