Format

Send to

Choose Destination
Hematology. 2004 Jun;9(3):223-33.

Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors.

Author information

1
Division of Medical Genetics, University of Washington, Seattle 98195, USA. huacao@u.washington.edu

Abstract

A number of pharmacological agents are currently available for the induction of the fetal hemoglobin (Hb F) to treat the patients with sickle cell disease and beta-thalassemia. In the present review, we summarized the investigation and development of these Hb F-inducing agents and introduced histone deacetylase inhibitors as the new strategy to induce Hb F to treat the hemoglobin disorders.

PMID:
15204104
DOI:
10.1080/10245330410001701512
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center