Objective: To observe the effect of brachytherapy of 125I implantation on localized prostate cancer.
Methods: Two-step technique was engaged in the implantation of 125I into the prostate for 41 localized prostate cancer patients. The prescription dosage of 125I was 160 Gy. TRUS and C-Arm X-ray were used for the confirmation of seeds location in the prostate.
Results: Thirty-three patients were followed up for 3 to 4 years. Abnormal PSAs were found in 2 patients by positive biopsy. No patients died in this investigation. The early stage complications were urinary irritation symptoms that were severe within 6 months and disappeared after 1 year.
Conclusion: Brachytherapy of 125I implantation increases long-term tumor-free survival rate, with few long-term complications and some short-tern urinary stimulating symptoms.