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J Womens Health (Larchmt). 2004 May;13(4):427-30.

Estrogen bioassay of ginseng extract and ArginMax, a nutritional supplement for the enhancement of female sexual function.

Author information

1
Department of Gynecology/Obstetrics, Stanford University School of Medicine, Stanford, California, USA.

Abstract

PURPOSE:

To determine whether ArginMax (The Daily Wellness Co., Sunnyvale, CA) or the Panax ginseng extract it contains has any estrogenic activity. ArginMax for Women, a nutritional supplement for optimization of sexual health, contains L-arginine, ginseng, ginkgo, damiana, multivitamins, and minerals.

METHODS:

A human endometrial adenocarcinoma cell line, Ishikawa, which contains an alkaline phosphatase (AP) enzyme sensitive to estrogen stimulation, was used in a bioassay to determine whether Panax ginseng or ArginMax contained estrogenic components.

RESULTS:

Neither ArginMax nor Panax ginseng stimulated AP at any of the concentrations tested.

CONCLUSIONS:

No estrogenic activity was evident in the sample of Panax ginseng extract tested or in a sample of ArginMax containing this extract in combination with other ingredients.

PMID:
15186659
DOI:
10.1089/154099904323087114
[Indexed for MEDLINE]

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