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Front Neuroendocrinol. 2004 Apr;25(1):1-26.

The polyglutamine tract of androgen receptor: from functions to dysfunctions in motor neurons.

Author information

1
Institute of Endocrinology, Centre of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy. Angelo.Poletti@unimi.it

Abstract

This review summarizes the mechanisms of neurotoxicity associated to androgen receptor containing an elongated polyglutamine tract responsible for motor neuronal cell death.

PMID:
15183036
DOI:
10.1016/j.yfrne.2004.03.001
[Indexed for MEDLINE]

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