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J Clin Invest. 2004 Jun;113(11):1515-25.

Progress on new vaccine strategies for the immunotherapy and prevention of cancer.

Author information

1
Molecular Immunogenetics and Vaccine Research Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA. berzofsk@helix.nih.gov

Abstract

In recent years, great strides in understanding and regulating the immune system have led to new hope for harnessing its exquisite specificity to destroy cancer cells without affecting normal tissues. This review examines the fundamental immunologic advances and the novel vaccine strategies arising from these advances, as well as the early clinical trials studying new approaches to treat or prevent cancer.

PMID:
15173875
PMCID:
PMC419494
DOI:
10.1172/JCI21926
[Indexed for MEDLINE]
Free PMC Article

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