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Ann Pharmacother. 2004 Jul-Aug;38(7-8):1297-300. Epub 2004 Jun 1.

Relationship between MMR vaccine and autism.

Author information

  • 1Clinical Sciences Department, College of Pharmacy Services, University of Michigan Health System, Ann Arbor, MI 48109-0221, USA. kriklein@umich.edu

Abstract

OBJECTIVE:

To evaluate the proposed link between the administration of the measles, mumps, and rubella (MMR) vaccine and the development of autism.

DATA SOURCES:

A literature search utilizing MEDLINE (1966-November 2003), with the key terms measles, mumps, rubella, and autism, was conducted. Review of the references listed in the articles identified was also performed.

DATA SYNTHESIS:

Ten articles that specifically evaluated the possible relationship between the MMR vaccine and autism were identified. Review articles, commentaries, and evaluations of a link between gastrointestinal symptoms in autistic children and MMR immunization were excluded.

CONCLUSIONS:

Based upon the current literature, it appears that there is no relationship between MMR vaccination and the development of autism.

PMID:
15173555
DOI:
10.1345/aph.1D293
[PubMed - indexed for MEDLINE]
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